Xylitol pastilles for everyone, from baby to elderly people. We manufacture our xylitol pastilles in our own production facility in Kitee, Finland. The xylitol pastilles are made in different flavours. Wild berry powders are used in lingonberry, sea buckthorn, bilberry (wild blueberry) and black currant powders and pastilles.
Taste arises from tooth-friendly xylitol, Finnish berry-powders and natural flavourings. Preparation also contains calcium, which is good for dental health and enamel. Recommended dose of xylitol for teeth is 5 g per day which you get from 6 pastilles.
Each pastille contains 800 mg of xylitol a binder and a lubricant. There is also added calsiumphosphate to improve remineralization of tooth enamel. Colourants are not used, all colours are from Finnish wild berry powders. There are 110 to 120 pastilles in 100g package.
Xylitol is naturally occurring in small amounts in fruits and berries. It can be produced from beech, birch and corn. It is used as a sugar substite such as toothpaste, pastilles, chewing gum and a household sweetener. It can also be use in baking.
Xylitol protects teeth from cavities and is a healthier alternative to normal sugar. Use xylitol after every meal of snack to prevent tooth mineralisation and cavities. It also increase salivation and helping dry mouth.
Xylitol has negligible effects on blood sugar because it is metabolized independently of insulin and has low glycemic index. It absorbed more slowly than sugar and xylitol supplies about 35 % fewer calories than basic table sugar. Because of that, it is better option with diabetes or weight problems.
New studies of children in Finland appeared that xylitol has moderate effect in preventing ear aches in healthy children. Daily use of xylitol can prevent 40% of ear infections.
Recommended daily dose of xylitol is 5 g, which means 6 pastilles der day.
Xylitol may have an laxative effect. Avoid that by taking pastilles several times a day, small dose at a time.
Xylitol (birch sugar) molecular weight is 152,15 g/mol and the empirical formula is C5H12O5 (Fig 1). Melting point of xylitol is 92 – 96 degrees Celsius. In 50 %-wt. agueous solution it’s acidity varies from 5,0 to 7,0. The acidity of the xylitol solution depends on the manufacturing method. Usually wood-based xylitol is more basic than xylitol made from other raw materials.
Xylitol is a natural sweetener. Xylitol is prepared from hemicellulose of plants, like deciduous tree, corn straw, rice straw, reeds or seed husk. These contain about 25% - 35% of xylane which can be converted in hydrolysis to xylose. Xylose acts as a starting material for the preparation of xylitol. In the process, xylose is hydrogenated to xylitol and xylitol crystals are obtained at the end of the process (Bond, 2009).
Other sugar alcohols in the pure xylitol may be less than 2.0% and a pure xylitol content is over 98% in the raw material (JP XV; USP32-NF27).
General impurities among xylitol are mannitol, sorbitol and galactitol. The E-code for xylitol as an additive in food is E967.
In xylitol pastilles, the main raw material is the xylitol and it’s %-weightmass is reported in the preparation (e.g., xylitol sweetener 94% indicates that 94 g of xylitol have been used per 100 g of product).
Pure xylitol is extremely stable at least 3 years if it is kept under 65% humidity and 25 degrees Celsius. Direct compression xylitol can form clumps during storage and therefore it should be processed into finished products within 9-12 months. Caking happens due to hygroscopicity of xylitol.
Xylitol solutions have been reported to be very stable. Xylitol is microbiologically well preserved because it doesn't ferment and microbiological spoilage does not occur easily or at all (Mäkinen 1981).
In pharmaceuticals and food preparations, xylitol is classified as non-toxic, non-allergic and non-irritant substance. WHO has not set a daily intake recommendation for xylitol because it is considered a safe substance for the humans. Most people can take up to 20-30 grams of xylitol as a single dose or 0.5 to 1.0 grams per kilogram of body weight during the day without any problems (Bond, 2009). In intestinal system 50% - 75% of xylitol dose is absorbed. Intestinal flora metabolizes xylitol and can cause some users to have stomach problems such as diarrhoea or flatulence.
Compressing neat xylitol into xylitol pastilles – or tablet is challenging and the crushing strength of neat xylitol is usually very weak. That's why xylitol has many direct compression qualities where the xylitol is granulated with a binder, like polydextrose or cellulose derivatives. These direct compression xylitol has a better compressibility and processability than 100% xylitol. The neat xylitol tablet with diameter of 12,5mm has a crushing strength of 40 N when compressed with 20KN force. Direct compression xylitol has crushing strength of 160N or more with a smaller compression force (Bond, 2009).
Xylitol is mainly used as a tooth-friendly sweetener in food-, hygiene-, and pharmaceutical industry. Xylitol sweetness is the same as for a normal sugar. Typical xylitol usage in food industry is xylitol pastilles and chewing gums, sweetener and sugar substitute in baking. Typical pharmaceutical usages are tablets, coatings and solutions where xylitol works as an excipient In hygiene products xylitol is used in mouthwash and toothpaste which prevent caries. In cosmetic industry xylitol is used in many kinds of lotions and creams where xylitol may be used to bind moisture and soften the skin's top layers.
Xylitol does not ferment into acids, so it is tooth-friendly. In addition, xylitol has been found to inhibit the growth of the Streptococcus Mutans bacteria which contributes tooth decay (Hayes, Mäkinen 1996).
Narskuttelu Oy started making xylitol pastilles in 2016. Previously, the eccentric tablet machine was in the production of medicinal carbon tablets in the pharmaceutical industry. The tablet machine has been taken into pharmaceutical production in early 1960s. At the end of Leiras pharmaceutical operations in Finland, a tablet machine weighing about 600 kg ended up in a pharmacy in Central Finland. In Central Finland, the local pharmacy was supposed to start manufacturing nutraceuticals, but the machine was waiting for the store.
The autumn 2015 tablet machine had to end up in a smelter when a pharmacist retired and the tablet machine was looking for a new home. The pharmacy staff knew Pekka from Narskuttelu Oy, who has been engaged with tablet machines in the pharmaceutical industry and university. Reconstructing an old tablet machine, searching for operating settings, and getting the device up and running took about a year in the garage. This was a very interesting time to familiarize yourself with the mechanics of the old machine and its operating principle.
After that, Narskuttelu Oy decided to start manufacturing its own self-made xylitol pastes with a variety of flavours, in the new food space in its own garage in autumn 2017. In 2018, the tablet machine moved to a clean room built in the industrial hall, where we are now operating in Kitee. The tablet machine produces xylitol pastilles about 10 kg per hour and is predominantly in product development testing for the compressibility of raw materials and blends. In xylitol compression experiments the machine is excellent because the machine requires only 10 grams of sample and only about 50-100 grams in the industrial test. New rotary tablet machines require 1 to 3 kg of mass to easily find compression adjustments.
Compression of the eccentric machine takes place only with the upper punch, which compresses the xylitol in the die. The lower punch is only involved by removing the compressed xylitol pastille from the die (See the video clip below).
On a rotary tablet machine, xylitol mass ends up in a die on a rotating table. The table rotates about 30 - 60 times per minute around its axis and the punches can be between 8 and 32 in the machine. The upper and lower punches are used to compress the pastille and a lower punch eject the pastille out from the die.
Rotary tablet machines have displaced eccentric tablet machines e.g. in the pharmaceutical industry due to their higher hourly output. A small rotary tablet machine can compress easily 30 kg of pastilles per hour without compromising on the quality of the pastilles (See the video clip below).
Xylitol is not suitable for dogs or other pets. Xylitol causes pet animals, especially for dogs, to lower blood sugar levels (hypoglycemia) and high doses of xylitol can damage the liver. The mechanism by which liver toxicity to the dog is produced is still unclear (Xylitol-Veterinary-Toxicology, Gwaltney-Brant, SM). Hypoglycemia is caused by a strong release of insulin into the bloodstream of the dog, which lowers sugar level in bloodstream.
If your dog is eating xylitol, contact your vet immediately.
The symptoms of dog hypoglycemia usually start within 30 minutes of taking xylitol and can continue for up to 12 to 18 hours because xylitol is slowly absorbed from the dog's intestine, especially from chewing gum preparations. Typical symptoms of hypoglycemia in the dog are vomiting, weakness, sluggishness, disturbances in the coordination of intentional movements, despair, tremor and loss of blood in the blood of the dog. Liver problems usually start within 24 to 48 hours of eating xylitol, but liver enzyme elevation can be detected earlier in the dog's blood test.
Narskuttelu xylitol pastille contains 800 mg of xylitol. Estimate how many xylitol pastilles your pet has eaten and report this to your veterinarian. With this information, the veterinarian knows how to treat your pet. Hypoglycemia in dogs may occur at a low dose of 50 to 100 mg xylitol per kg bodyweight of dog.
Magnesium stearate (e470) ([CH3(CH2)16COO]2Mg, Mw 591,24 g/mol) is one of the most widely used tablet machine glidants in the world. Magnesium stearate is a salt consisting of magnesium cation and two stearate fatty acids. Some of the stearates may also be a palmitate (Allen and Luner, 2009). The concentration of magnesium in the megnesiumstearate powder must be between 4% and 5% in the final products.
The magnesium stearate has a melting point of 117-150 degrees Celsius. Magnesium stearate has been found three different crystalline forms, i.e. anhydrate, hydrate, and trihydrate. Commercially approved products may contain less than 6% moisture. The true density of Magnesium Stearate is approx. 1.09 g / cm3 and the pour density is about 0.16 g / cm3. The powder flow is very poor and the material is very cohesive. The material feels greasy on the fingertips and easily adheres to the skin. Magnesium stearate is practically insoluble in water and in ethanol.
Magnesium stearate can be prepared by using magnesium hydroxide or magnesium oxide as the starting material which reacts with the stearate fatty acid or salt, depending on which production method has been used.
The fatty acid may be animal or plant based (Allen and Luner, 2009). In practice, all magnesium stearate lubricants today are derived from palm, rapeseed or cotton oil. Narskuttelu Oy currently uses magnesium stearate made from palm oil or rapeseed.
Magnesium stearate is widely used in the food, cosmetics and pharmaceutical industries at concentrations ranging from 0.25% to 5% of the composition.
In the production of xylitol pastilles, magnesium stearate prevents either the adhesion of the pressed mass to the metal surfaces or the friction between the punch and the mold.
Carboxymethylcellulose acts as a binder in xylitol. Due to the poor compressibility of xylitol, the direct compression xylitol powder is granulated with carboxymethyl cellulose. Carboxymethylcellulose improves the powder flow of xylitol in a tablet machine and increases the formation of bonds in the compression step, whereby xylitol is compressed into a pastille with a reduced compression force. As a binder in tablet and pastille formulations, carboxymethylcellulose is used in a range of about 1 to 2% of the composition, depending on the molecular size of the carboxymethylcellulose used.
Polydextrose is used as a binder in xylitol granules instead of carboxymethylcellulose. Polydextrose has no melting point because it is an amorphous (non-crystalline) excipient. The glass transition point of polydextrose is about 150 to 160 degrees Celsius which means transformation from a glassy to a liquid state. As a binder in tablet and pastille preparations, polydextrose is used between 1 and 2% of the composition.
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DELIVERY AND RETURNING POLICY
The delivery can be expected within 2 to 4 business days from the dispatch date. The used delivery company is GLS Finland.
If the product does not meet your expectations, you may return or exchange it within 14 days of receiving it. If the packages of xylitol or dental products have been opened we do not return the full refund. You are responsible for the cost of returning the goods. You are also responsible for returning the goods to us in order to receive a full refund.
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